Tags: Express FCGeorge Ssemwogereresam simbwaStarTimes Uganda Premeir LeaguetopURA FC URA drew 1-1 with Bul in their last game (file photo)StarTimes Uganda Premier LeagueURA FC vs Express FC Mandela National Stadium, NambooleTuesday, 26-03-2019 @4pmNAMBOOLE – URA FC may be without influential captain Shafick Kagimu when they host Express FC in the StarTimes Uganda Premier League on Tuesday afternoon. Kagimu who is the Tax Collectors’ top scorer this season suffered a knock in their last game against Bul FC on Friday and he is yet to recover fully. Defender Patrick Mbowa is suspended due to accumulation of yellow cards and joins the trio of Nyakoojo Benjamin, Nyanzi Abudallah and Allan Mugalu who are all still out injured.Express will still be without Eric Kambale who has had an injury troubled first season with the Red Eagles. Pius Mbidde and Muwanga are also out of Tuesday’s game with injuries. The Good news for Express is that Frank ‘Zaga’ Tumwesigye, Tony Odur and Brian Umony have recovered in time to face URA.What the coaches are saying:Sam Simbwa, URA FC.“We have prepared very well for the Express game. We played Bul on Friday so we had little time to prepare for this one but the boys are ready to go.“We have respect for Express because they are one of the traditional teams but we don’t fear them.“I expect my team to win and go into third at the end of the day.George Ssemwogerere, Express FC.“We have had enough time to train ahead of the game because we were in the international break.“The boys are in good spirits and some of the injured players are on the road to recovery.“I watched URA and i am sure it is a team that gives u a chances to attack and defend against them due to their system of play. We will go out to attack them.URA missed a chance to go third on Friday when they drew 1-1 at home to Bul despite scoring inside the first minute.On Tuesday, another opportunity presents its self in form of Express that have been struggling all season. A win on Friday will see URA move onto 42 points, one ahead of Onduparaka who take on SC Villa on Wednesday.The Red Eagles find them selves in 11th on the standings with 29 points, 9 ahead of Ndejje University who occupy the last of the three relegation spots.Despite Ssemwogerere claiming that they are not concerned by what is going on below them, a loss against URA coupled by positive results for the teams occupying 12th-14th, may see the Red Eagles dragged into the dog fight for the second season running.Match Facts:This will be the 18th top flight meeting between URA and Express since April 2011.In the other 17 within that period, URA have won six, lost two and drawn 9 against the Red Eagles.However, the Tax Collectors have gone 7 games minus victory against Express with their last triumph coming in the 2-1 win at Wankulukuku back in May 2015.Both sides drew 0-0 at Wankulukuku at the start of the season and also shared spoils (1-1) in the reverse fixture last campaign.URA head into Friday’s game unbeaten in their last five League games (W3 D2). Their last loss was in the 1-0 defeat at home to Maroons on the 19th of February.However, at home, the Tax Collectors have won only two of their last six games (D2 L2). The two losses that they have suffered in that period are the only ones they have succumbed to all season.For Express, they come into the game having won only two of their last 10 League games (D4 L4).Away from home, the Red Eagles have also won only two of their last 9 (D2 L5).The other game on Tuesday.-Tooro United FC vs Bul FCComments
The McKinleyville 8-10 Little League All-Stars clinched the district and section championships this past week, advancing to this weekend’s Northern California state tournament in Palo Alto.The Mack All-Stars opened play at the state tourney against Porterville on Saturday, falling 10-3.They will try to rebound against Fair Oaks Orangevale this afternoon at 4 p.m.
51; Zip codes – those five- or nine-digit numbers on mail – have an analogue in every one of your cells. Like a city,1 a cell has information to ship from place to place.2 To make sure that the manufacturing instructions for protein parts arrive at the appropriate assembly site, the shipper puts a molecular tag on a transport vehicle (the postman) that works just like a zip code. At least that is the way an article in PLoS Biology described the process. Richard Robinson is a freelance science writer who wrote in the peer-reviewed, open-access science journal PLoS Biology about “A Two-Step Process Gets mRNA Loaded and Ready to Go.”3 (mRNA refers to the messenger RNA, the edited transcript of DNA, that contains the coded instructions for a protein.) He used the word “zipcode” five times in his description of recent findings about the process:Proteins are the workhorses of the cell, but to get the most work out of them, they need to be in the right place. In neurons, for example, proteins needed at axons differ from those needed at dendrites, while in budding yeast cells, the daughter cell needs proteins the mother cell does not. In each case, one strategy for making sure a protein gets where it belongs is to shuttle its messenger RNA to the right spot before translating it. The destination for such an mRNA is encoded in a set of so-called “zipcode” elements, which loop out of the RNA string to link up with RNA-binding proteins. In yeast, these proteins join up with a myosin motor that taxis the complex to the encoded location.The players in this process are the messenger RNA (mRNA) with the coded instructions (like blueprints) for a molecular machine, the zipcode elements attached to the mRNA that tell it where it needs to go, and the myosin “taxi” that takes the mRNA to the right factory (ribosome) where the protein parts will be assembled. But other parts must be involved; who sorts the mail? Who checks that the zip code is present? The rest of Robinson’s synopsis discussed how recent findings show more complexity than previously known (see 06/26/2002, 09/06/2002, 01/01/2005, 01/13/2007). It was known that proteins called She2p and She3p were involved, but not how they interacted with the zipcode elements on the mRNA. There is a new level of quality control, he said, that has come to light:Based on their results, the authors propose a two-step model of transport complex formation. Within the nucleus, She2p binds to the mRNA as it is transcribed, and then shuttles it to the cytoplasm. She2p binds loosely and promiscuously, though, catching up mRNAs both with and without zipcodes. Once in the cytoplasm, She3p joins on, tightening the grip on mRNAs that contain zipcodes while booting out those without them. With the myosin motor attached to She3p, the complex motors off to its destination elsewhere in the cell. The results in this study indicate that quality control in mRNA transport relies on a reciprocal action: the complex proteins together ensure that only those mRNAs with a destination tag are incorporated into the transport complex, and the mRNA, by binding to each of the proteins in the complex, ensures that all are on board before the journey starts.In other words, one protein (She2p) binds to the parcel inside the nucleus and takes it outside, where the other protein (She3p) recognizes its counterpart, checks the zipcode, and joins the transport complex to the myosin taxi. Studies have shown that without this quality-control mechanism, like when She2p mutated to prevent it joining with the mRNA, “the ability of the RNA�protein complex to reach its destination was impaired.” Robinson’s comments referred to a paper by Muller et al in PLoS Biology.4 The authors stated, “We propose that coupling of specific mRNA recognition and assembly of stable transport complexes constitutes a critical quality control step to ensure that only target mRNAs are transported.” They also used the phrase “zip code” 68 times, but never mentioned evolution once, except obliquely in one figure, to show phylogenetic comparisons of She3p between different species of yeast.1. Michael Denton compared the cell to a city in a memorable chapter of his 1985 book, Evolution: A Theory in Crisis, p. 328. His description began, “To grasp the reality of life as it has been revealed by molecular biology, we must magnify a cell a thousand million times until it is twenty kilometres in diameter and resembles a giant airship large enough to cover a great city like London or New York. What we would then see would be an object of unparalleled complexity and adaptive design…. a world of supreme technology and bewildering complexity.”2. Ibid., “A huge range of products and raw materials and raw materials would shuttle along all the manifold conduits in a highly ordered fashion to and from all the various assembly plants in the outer regions of the cell.”3. Richard Robinson, “A Two-Step Process Gets mRNA Loaded and Ready to Go,” Public Library of Science: Biology, 9(4): e1001047. doi:10.1371/journal.pbio.1001047.4. M�ller M, Gerhard Heym R, Mayer A, Kramer K, Schmid M, et al. (2011), “A Cytoplasmic Complex Mediates Specific mRNA Recognition and Localization in Yeast,” doi:10.1371/journal.pbio.1000611.The guys who make up stories about life originating from primordial soup don’t think of any of these things. They get all excited if they find a strand of RNA that can make one simple chemical reaction occur, as if that’s all that is needed. But give them the best case scenario: a primitive cell filled with the essential molecules of life, but no process for getting the molecules where they are needed. That includes no quality control, no inspections, no checks and balances, no feedback, no networks. What will happen? Entropy. We remind our readers that evolutionary theory provided nothing to this scientific discovery. We also remind them that these complex processes were described not for the most complicated eukaryotes, like giraffes, but ones much more humble: yeast.(Visited 17 times, 1 visits today)FacebookTwitterPinterestSave分享0
Millions of people around the world willmark ‘Earth Hour’ by switching off their lights in a bid to highlight the need to conserve energy. (Image: Earth Hour) Khanyi MagubaneSouth Africa will be joining 1 189 cities and towns across the world to mark Earth Hour, when all participating households and businesses will switch off the lights for an hour on 28 March. Cape Town, Johannesburg, Durban, Franschhoek and Stellenbosch are part of 39 cities and towns that will be celebrating Earth Hour in South Africa, which will start from 8:30pm and last until 9:30pm.Organised by the conservation group World Wildlife Fund (WWF), the event has already far exceeded the ambitious target of 1 000 cities in 25 time zones set out by the organisation.Morné Du Plessis, the Chief Executive Officer of WWF South Africa says he’s excited by South Africa’s involvement in the campaign,“There’s a palpable excitement about this event. Not just because it’s a massive global undertaking involving millions of people, but because it deals with a very important issue, namely the need for global action on climate change.”To mark this historic event, millions of people across the globe will gather in parks, streets, town squares and homes to watch the lights going out on iconic landmarks and city skyscrapers.Popular landmarks around the world such as Cape Town’s Table Mountain, Australia’s Sydney Opera House, the Wat Arun Buddhist temple in Bangkok, the Coliseum in Rome, Stockholm’s Royal Castle, London’s City Hall, New York’s Empire State Building, Sears Tower in Chicago and the Golden Gate Bridge in San Francisco will all shut down for an hour.Influential companies have also jumped on the bandwagon and are now encouraging their clients to join in this campaign.Internet search engine Google will also switch off for on hour in solidarity with the campaign.Users of the blackberry mobile business phone have also been asked to turn off their phones for an hour.Fighting global warmingThe first Earth Hour began in Sydney in 2007, when 2.2-million homes and businesses switched off their lights for a full 60 minutes.In 2008, the story of the event grew into a global one, when 50-million switched off their lights. This is the first time however, that that the campaign is now spread across the world in all continents.People of all ages, nationalities, race and background, will now have the ability to use something as simple as their light switch, to vote for saving the earth, instead of voting for global warming.It is hoped by WWF that every person who switches off their lights will be “vote earth” and each vote will be counted towards petition target of one billion votes, which will be presented to world leaders at the Global Climate Change Conference in Copenhagen later this year. At this meeting, official government policies to be used to take action against global warming will be determined. These will replace the Kyoto Protocol.To spread the message, a vigorous marketing campaign, mostly carried out by the media and through social networks such Facebook and Twitter, was carried out.Eskom going greenIn keeping in line with the global event, South Africa’s electricity utility Eskom has called all South Africans to participate in the worldwide climate change awareness programme.The parastatal says the national “switch off” event will form part of a tangible way of demonstrating solidarity and support for the Earth Hour global awareness campaign.“This will by far surpass the 2008 event, when people in 35 countries participated,” said Eskom corporate services Managing Director Steve Lennon in a statement released by the company.“As part of its support for the campaign, Eskom will be measuring the reduction of electricity used during the hour against typical consumption for this time on an average Saturday evening,” he said. According to Lennon, turning off the lights for an hour in South Africa, will benefit the country, as hundreds of tons of coal will be saved from burning to produce electricity.Lennon said that every kilowatt-hour of electricity saved amounts to a reduction in carbon dioxide emissions of one kilogram.In a bid to decrease its carbon footprint, the electricity utility has adopted a six-point climate change plan that commits it to reduce its greenhouse gas emissions in South Africa.The plan will concentrate on using lower carbon-emitting technologies; adopting energy efficiency measures to reduce demand for electricity as well as greenhouse gases and other emissions.The plan will also adapt to the impacts of climate change; innovating changes through research, demonstration and development; investing in carbon credit market mechanisms, and making progress in climate change mechanisms through advocacy, partnerships and collaboration.“As South Africa’s primary supplier of electricity, we believe Earth Hour is an initiative we must support as it underlines our key role as a supplier of electricity and the active role that all South Africans can play in reducing demand for electricity,” Lennon concluded.South Africa joining the worldTo celebrate Earth Hour, a free “Concert in the Dark” will take place at the popular V&A Waterfront in Cape Town.The event will coincide with the Mother City’s iconic landmark, Table Mountain having its lights turned off for an hour.The concert, sponsored by Philips Lighting SA, will include boast a performance by the Cape Philharmonic Orchestra (CPO), which will play for free, in support of Earth Hour.A marimba group Ethnic Rhythm will also supply music on that night.Speaking on its involvement in the campaign, CEO of the Cape Philharmonic Louis Heyneman said, “It is an honour for the CPO to make its contribution to a global initiative like Earth Hour, and to present the power of music in a different light.”The orchestra will play a repertoire including a number of light classics such as, Von Suppe’s Light Cavalry Overture, Johan Strauss II’s Blue Danube Waltz, and Johannes Brahms’s Hungarian Waltz No 5.Do you have comments or queries about this article? Email Khanyi Magubane at [email protected] Related articlesGreenpeace takes on Africa Green lifestyle magazine for SA Climate park to cool off animals Power from the South African sun Green airline goes greener Useful linksEarth Hour –Earth Hour – South AfricaWWF – South AfricaCape Philharmonic Orchestra
Essential Reading! Get my 2nd book: The Lost Art of Closing “In The Lost Art of Closing, Anthony proves that the final commitment can actually be one of the easiest parts of the sales process—if you’ve set it up properly with other commitments that have to happen long before the close. The key is to lead customers through a series of necessary steps designed to prevent a purchase stall.” Buy Now Let’s say you and your competitors both sell the same thing to your customers. You both buy the same raw materials to develop your product. You both pay $100 for those raw materials. You sell your product for $150, and your competitor sells theirs for $130. Your higher price is enough to cause some buyers to buy from your competitor. All things being equal, they’re right to pay the lower price.But all things are not equal. The product that you sell is superior to your competitor’s. You invest more to develop the final product, it is of far superior quality, it lasts longer, and your customers don’t have to buy it as frequently. More still, your sales team is out teaching your customers how to get even more out of the product and saving them money. Your competitor has a lower price, but you have a lower cost. Why? because you create greater value.But you lose a significant amount of deals to your competitor. Some prospects don’t understand how paying more can cost them less. You are faced with a choice. You can either more effectively sell the value you create, or you can eliminate price as an objection. It’s easier to lower your price than it is to sell better.You match the $130. Now you have less profit to support your sales model, and you can no longer spend time teaching your clients how to save money. You also have less money to develop the product the way you had been, and so you and your competitor are now equal.But every action has an equal and opposite reaction. Your competitor was selling lowest price. That was their business strategy. So they lower their price to $120, taking back the price advantage on which they were competing. Your customers still demand the same level of service and support, and you don’t understand how your competitor can deliver anything of value at that price. But now you’ve given up competing on the greater value you create, so you match the $120, imagining there is no way your competitor can lower their price again. But you are wrong. They lower their price to $110.This is how sales organizations, salespeople, and whole industries are commoditized. If you have chosen low price as your strategy, then you need to compete by eliminating costs and providing the lowest price in all cases. But if you have decided to sell the additional value you create, the value that makes you different, then you need to focus on selling more effectively.Reducing your price to increase your revenue is one way to go about increased sales. But that choice comes with reduced margins. You may indeed end up increasing your sales and selling more while building a far less profitable, and less valuable business. And you might also build a business that doesn’t make a difference in the end.
Essential Reading! Get my 3rd book: Eat Their Lunch “The first ever playbook for B2B salespeople on how to win clients and customers who are already being serviced by your competition.” Buy Now Would you give up your comfort for the discomfort of looking at ideas and beliefs you disagree with if it meant new choices and new results? Could you give up your strongest held beliefs?Would you give up your experience and your ability to take the role of beginner? Would you assume the role of student? Is it possible to give up what you have learned to take in new information and gain new experiences?Could you abandon the habits you’ve developed over a lifetime and trade them in for new habits, even if it meant devoting yourself to building them over the next 6 months? If this is what you had to do to have what you really want, could you?Are you willing to try something new even if you risked failing—or even embarrassing yourself in the process of practicing something necessary to move you closer to your goals?Will you give yourself the same advice you would give others if they needed to embrace the discomfort of ideas they don’t like, give up the competencies they’ve gained over time, develop new and difficult to run in habits, and risk failing and maybe even a loss of face if it meant they would attain their goals.If what you are doing now was enough for you to meet your goals, you would already have those goals. You can have anything you want, provided you are willing to pay the price and persist long enough to have it. Part of paying that price means giving up your comfort, your beliefs, your experience, and your habits. It means you take on new information, even information, ideas, and beliefs you have resisted—and maybe vehemently and publicly opposed.To have what you want, you don’t have to give anything, but you do have to give what is necessary—and what is necessary isn’t always easy to give.
India’s Harika Dronavalli clinched the bronze medal in the women’s individual chess at the Asian Games, in Guangzhou on Tuesday.Chinese top seed Hou Yifan won the gold, while compatriot Zhao Xue got the silver.Harika, with five wins, three draws and one loss, scored 6.5 points to grab the third spot.Grand Master Yifan won eight rounds and drew one to score 8.5 points. And Xue, also a grand master, won seven matches, drew one and lost one to finish with 7.5 points.Meanwhile, another Indian women’s player Tania Sachdev could earn only 5.5 points with five wins, one draw and three losses, to finish on sixth position.
MOST READ In 1994, he won the Consejo Mundial de Lucha Libre world heavyweight title. Gonzalez competed in World Championship Wrestling between 1997 and 2000, and during 2001-2006 used the ring name Black Tiger III. He went back to being Silver King after he was unmasked during a 2006 match.Sports Related Videospowered by AdSparcRead Next Panelo: Duterte ‘angry’ with SEA Games hosting hassles Gonzalez was struggling to stand up from the first flooring when another blow from Juventud Guerrera sent him sprawling back down front first, the Press Association said. The victorious Young Warrior pinned Silver King and started celebrating his win, the news agency said.Attendee Roberto Carrera Maldonado told the BBC the wrestler’s condition initially appeared “staged” as part of the fight, before efforts were made to revive him and the audience was cleared from the venue.“All of us were really shocked. It wasn’t clear what was happening,” Maldonado said. “I had the impression they didn’t know what to do.”The London Ambulance Service said medics arrived five minutes after they were called to the Roundhouse on Saturday, but the patient was pronounced dead at the scene.Gonzalez was the son of well-known Mexican wrestler who performed as Dr. Wagner, and one of his brothers is luchador Dr. Wagner Jr. He made his professional debut in the mid-1980s and worked for promoters in Mexico and Japan.ADVERTISEMENT LATEST STORIES Private companies step in to help SEA Games hosting In this image made from video taken on Saturday, May 11, 2019, The Silver King, right, talks to the camera with fan Mark van der Enden at the Roundhouse in London. A fan of a wrestler and actor who died after collapsing on stage mid-performance in London shared the moment he got to meet his idol earlier that afternoon. Cesar Cuauhtemoc Gonzalez Barron, also known by his wrestling title of Silver King, died of a suspected heart attack at the Roundhouse in London’s Camden on Saturday night, promoters said. (@estefyunvin via AP)LONDON — A well-known Mexican wrestler who co-starred in the film comedy “Nacho Libre” died in London after he collapsed during a match that a witness described as so elaborately staged it wasn’t immediately clear something seriously was wrong.Cesar Cuauhtemoc Gonzalez Barron, who wrestled with the ring name Silver King, was one of the featured wrestlers of “The Greatest Show of Lucha Libre” on Saturday night. The north London performance venue, the Roundhouse, tweeted just after 12:30 a.m. Sunday that the 51-year-old “sadly lost his life” during the event.ADVERTISEMENT Don’t miss out on the latest news and information. Lucha Libre World, which promoted the Roundhouse event, said in a statement the lucha libre star “suffered what we believe was a cardiac arrest while performing in the show and sadly passed away.”Gonzalez appeared as a champion wrestler and comic villain in the 2006 movie “Nacho Libre”, which starred Jack Black as a monk who wants to be a masked luchador. Lucha libre is a popular form of wrestling in Mexico that features colorful masks, elaborate costumes and acrobatic techniques.FEATURED STORIESSPORTSPrivate companies step in to help SEA Games hostingSPORTSPalace wants Cayetano’s PHISGOC Foundation probed over corruption chargesSPORTSSingapore latest to raise issue on SEA Games food, logisticsThe description of the show on the Roundhouse’s website said the “awesome and immense Silver King” would take to the ring “portraying his villainous character, the evil rudo Ramses from his role” in the movie.Britain’s Press Association reported that Gonzalez’s opponent, Juventud Guerrera (Spanish for “Youth Warrior”) knocked him to the canvas twice. Cayetano: Senate, Drilon to be blamed for SEA Games mess Philippine Arena Interchange inaugurated SEA Games hosting troubles anger Duterte DA eyes importing ‘galunggong’ anew Ethel Booba twits Mocha over 2 toilets in one cubicle at SEA Games venue Trending Articles PLAY LIST 00:50Trending Articles00:50Trending Articles02:25Cayetano’s beef with ABS CBN? Unfair air time during 2016 campaign02:42PH underwater hockey team aims to make waves in SEA Games01:44Philippines marks anniversary of massacre with calls for justice01:19Fire erupts in Barangay Tatalon in Quezon City01:07Trump talks impeachment while meeting NCAA athletes02:49World-class track facilities installed at NCC for SEA Games02:11Trump awards medals to Jon Voight, Alison Krauss Kawhi Leonard for the win as Raptors escape 76ers for East finals ticket Hontiveros presses for security audit of national power grid View comments